organization logo


Frank Scarano 
Northeast Branch - American Society for Microbiology or    508-999-9239 


Tuesday April 24, 2012 from 6:00 PM to 9:30 PM EDT

Add to my calendar 


Johnson and Wales Inn 
213 Taunton Avenue
Seekonk, MA 02771

Driving Directions 
 A New Approach to Microbial Pathogenesis:
The Damage-Response Framework
Liise-anne Pirofski, M.D.
Professor of Medicine, Microbiology and Immunology
Division of Infectious Diseases
Albert Einstein College of Medicine
Bronx, New York
Tuesday, April 24, 2012
Hosted by:
The Northeast Branch, American Society for Microbiology
University of Massachusetts Dartmouth, Department of Medical Laboratory Science Student Association
Evening Program:

Dr. Pirofski is currently Professor of medicine, microbiology and immunology at Albert Einstein College of Medicine and Chief of the Division of Infectious Diseases at the College and at Montefiore Medical Center. Her research program is focused on immunity to encapsulated pathogens; in particular, mechanisms of resistance and susceptibility to such microbes in normal and immunocom-promised hosts and novel strategies for vaccine development, using Cryptococcus and pneumococcus as examples. Dr. Pirofski is also co-developer of the damage response framework of microbial pathogenesis.

This lecture presents a new way of looking at the problem of microbial pathogenesis that incorporates the contributions of both the microbe and the host and takes the view that there are no pathogens… just microbes and hosts. Furthermore, the states of microbial pathogenesis, namely commensalism, colonization, latency and disease are viewed to be continuous and to differ only in the amount of damage to the host. This framework makes it possible to understand microbial virulence in the context of the immune status of the host, eliminating the need to introduce qualifiers, exceptions and modifiers to explain why the same microbe can cause disease in one host, but not another. The damage framework can be used to classify microbes as a function of the amount of damage and the immune status of the host, a system that does not rely on specific definitions.


Dinner includes: Choice of Boneless Stuffed Chicken Breast, New England Baked Cod, or Grilled 6oz. Sirloin with Sautéed Mushrooms & Onions. Served with an Assortment of Fresh Vegetables & Dip, Cheese & Crackers, Garden Fresh Tossed Salad, Fresh Baked Rolls & Butter, Yukon Gold Mashed Potatoes, Green Beans with Roasted Red Peppers, and Vanilla Ice Cream with Chocolate Sauce. Also Freshly Brewed Coffee and Tea Service. A vegetarian option will be available.

        Social Hour   6:00 pm

      Dinner           6:30 pm

      Lecture          7:30 pm

Join the Northeast Branch or Renew your Membership here:



send a check made out to NEB-ASM for $15.00 (regular) or $10.00 (student) to
Irene George
PO Box 158
Dover, MA 02030