Where
Life Sciences Building (Busch Campus)145 Bevier Rd
Auditorium
Piscataway, NJ 08854
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Proteomics in Skin Care- Beyond Gene Expression for Claims Testing?
Karen Young, Michael Southall, Nava Dayan, Philip Wertz, Matt Kuruc
Proteins are vital part of the living organism controlling metabolic paths of cells. As with gene expression for mRNA, proteomics confirms the presence of a protein but unlike gene expression also assesses its post translational modification and therefore its functional relevancy. In recent years, gene expression analysis has been utilized to study the reactivity of certain treatments to skin. While gene expression provides some insights quantifying mRNA levels that deviate from normal, it may not be correlated with protein content. This means that it may not at all represent correct evaluation of bio-chemical cascades. It is now known that mRNA is not always translated to protein. In fact, the amount of protein produced for a given amount of mRNA depends on the gene it is transcribed from and on the current physiological state of the cell. This symposium brings together worldwide experts to discuss proteomics and metabolomics in general and applicability to skin research and product development.
Karen Young, CEO The Young Group - "Genome Mapping and the Beauty Consumer"
Before opening The Young Group in 1999, Karen was Vice President of Marketing, Advertising, Product Development and Sales Promotion for Lancôme. Prior to that, she spent seventeen years at Estée Lauder, where she held a variety of executive positions, including Executive Director of Color Cosmetics. Karen is an active board member of Fashion Group International. She is a certified personal trainer and nutritionist. Karen divides her time between New York and Paris, where The Young Group also has an office. Since opening The Young Group, Karen has worked extensively in all categories of the cosmetic industry. She has developed concepts and products for Smashbox, RoC, Bath and Body Works, Neutrogena, Colgate Palmolive, Vichy and Canyon Ranch. Karen has worked on numerous established brands in the beauty category, including Christian Dior Beauté, Shiseido, Parfums Givenchy, Avon and 3M Products.
Before opening The Young Group in 1999, Karen was Vice President of Marketing, Advertising, Product Development and Sales Promotion for Lancôme. Prior to that, she spent seventeen years at Estée Lauder, where she held a variety of executive positions, including Executive Director of Color Cosmetics. Karen is an active board member of Fashion Group International. She is a certified personal trainer and nutritionist. Karen divides her time between New York and Paris, where The Young Group also has an office. Since opening The Young Group, Karen has worked extensively in all categories of the cosmetic industry. She has developed concepts and products for Smashbox, RoC, Bath and Body Works, Neutrogena, Colgate Palmolive, Vichy and Canyon Ranch. Karen has worked on numerous established brands in the beauty category, including Christian Dior Beauté, Shiseido, Parfums Givenchy, Avon and 3M Products.Dr. Michael Southall, Research Director, Fellow, Research & Development Johnson & Johnson Consumer & Personal Products Worldwide (CPPW) - "Applications of Metabolomics: Metabolic signature of sun exposed skin suggests catabolic pathways overweighs anabolic pathways"
Dr. Michael Southall is a Research Director & Fellow of the Global Skin Biology & Pharmacology and Skin Care Innovation Platforms, Research & Development for Consumer & Personal Products Worldwide (CPPW), a unit of Johnson & Johnson Consumer Companies, Inc. In his position, Dr. Southall strives to develop a pipeline of technologies that are scientifically proven to provide safe and effective skincare benefits. He leads this department, overseeing almost all natural products development processes for Johnson & Johnson’s Beauty Care Brands. Prior to beginning his career at Johnson & Johnson (CPPW), Dr. Southall worked as an Analytical Chemist in the Department of Protein Chemistry, Telios Pharmaceuticals in La Jolla, California. He took part in drug discovery, purification, characterization and identification of peptides for use as medical devices for skin wound healing. He received his B.S. in Microbiology from the University of California in San Diego and his M.S. in Cellular Biology from George Mason University in Fairfax, Virginia. He went on to pursue his Ph.D. in Pharmacology at Indiana University School of Medicine in Indianapolis, where he also completed his Post Doctoral Fellowship in Dermatology.Nava Dayan, President, Dr. Nava Dayan L.L.C -Elastin and Tropoelastin in Skin Aging - "A Functional Proteomics Proposition"
Dr. Nava Dayan is the owner of Dr. Nava Dayan L.L.C, a skin science and research consultancy located at NJ, USA, and serving the pharmaceutical, cosmetic, and personal care industries; dermal and transdermal. Nava offers consulting for product feasibility in skin care, composition of R&D plans covering efficacy and toxicology; planning, execution and data interpretation into claims of experiments during the processes of drug discovery as well as formulations, delivery for improved efficacy and attenuated toxicity. Sample of expertise includes: drug-skin interaction, bio-markers (genomics and proteomics), skin/age related sensitivities, inflammatory skin disorders, innate immunity and biota. She also conducts customized education classes. Nava has 24 years of experience in the greater skin care segment, and have yielded more than 150 publication credits in numerous industry-respected journals and in four books. She has been awarded the In-Cosmetics Gold Award for innovation and commensurate recognition from the NYSCC and the CRS for excellence. Nava has a wide network of CRO’s with whom she is working to fine tune and execute R&D.
Dr. Nava Dayan is the owner of Dr. Nava Dayan L.L.C, a skin science and research consultancy located at NJ, USA, and serving the pharmaceutical, cosmetic, and personal care industries; dermal and transdermal. Nava offers consulting for product feasibility in skin care, composition of R&D plans covering efficacy and toxicology; planning, execution and data interpretation into claims of experiments during the processes of drug discovery as well as formulations, delivery for improved efficacy and attenuated toxicity. Sample of expertise includes: drug-skin interaction, bio-markers (genomics and proteomics), skin/age related sensitivities, inflammatory skin disorders, innate immunity and biota. She also conducts customized education classes. Nava has 24 years of experience in the greater skin care segment, and have yielded more than 150 publication credits in numerous industry-respected journals and in four books. She has been awarded the In-Cosmetics Gold Award for innovation and commensurate recognition from the NYSCC and the CRS for excellence. Nava has a wide network of CRO’s with whom she is working to fine tune and execute R&D.Philip Wertz, Ph.D. Professor; University of Iowa - “Pathways of Epidermal Lipid Biosynthesis”
Philip W. Wertz is a Professor in the Department of Oral Pathology, Radiology and Medicine at the University of Iowa and the Dows Institute. He earned his A.B. in biochemistry at Rutgers University and received a Ph.D. in biochemistry at the University of Wisconsin. After post-doctoral training at McArdle Laboratory for Cancer Research, Dr. Wertz was appointed Research Scientist at Marshall Dermatology Research Laboratories at the University of Iowa. In 1990 he was appointed Associate Professor at the University of Iowa College of Dentistry and in 1993 was promoted to present rank. Dr. Wertz’s research focuses on lipids and barrier function in skin and oral mucosa. He is a member of the Society for Investigative Dermatology, American Oil Chemists Society, American Society for Biochemistry and Molecular Biology, American Association for Dental Research and the American Association of Pharmaceutical Scientists (AAPS).
Matt Kuruc,Vice President of Business Development at Biotech Support Group - "New Functional & Chemical Proteomics Methods and Strategies"
Mr. Kuruc is the Vice President of Business Development at Biotech Support Group. He supports academic and commercial partnerships in addition to sales and marketing of a catalog of consumable research products.