Participation in the pilot is free. The window for submitting applications is July 2015 through October 11, 2015.

Participation in the pilot is free. However, any associated costs (e.g., travel, meals) are the responsibility of the individual participant. Participants will receive helpful performance feedback in the major content domains of the assessment.




Courtyard by Marriott 
Boston Downtown
275 Tremont Street
Boston, MA 02116, USA 

Chapel Hill

University of North Carolina, Chapel Hill
111 Mason Farm Road
Medical Biomolecular Research Building (MBRB)
Room 2204
Chapel Hill, NC 27599

New York

Icahn Mt. Sinai School of Medicine 
1468 Madison Avenue
Annenberg Building, 13th Floor
Room 1301
New York, NY 10029


JAH M13A-East, JAH M13B-West
Jefferson Alumni Hall Learning Resources Center
1020 Locust Street, Mezzanine Level
Philadelphia, PA 19107

Scott 306 and Scott 307
1020 Walnut Street
Philadelphia, PA 19107 

Washington, DC

Georgetown University School of Medicine
3900 Reservoir Road, NW
Preclinical Science Building
Room LA-6
Washington, DC 20007


If you have any questions or concerns, please contact us at


NBME Clinical Research Program Pilot Assessment

The National Board of Medical Examiners® (NBME®) is developing a Clinical Research Pilot Assessment to identify strengths as well as gaps in clinical research professionals' knowledge. The Pilot Assessment is designed to provide a baseline for a universally recognized, unbiased measure of the competence of clinical research professionals in the United States to perform safe, effective research in human subjects.

Participants who complete the Pilot Assessment will receive a $75.00 Amazon gift card and will also receive an opportunity to sit a future assessment free of charge in the Clinical Research Program, provided the program successfully launches. 


A major purpose of the pilot examination is for NBME to obtain feedback regarding the Clinical Research assessment. There is no guarantee that a participant will be able to start, or complete, any or all sections of the pilot examination. Rescheduling will not be possible if technical difficulties occur that prevent the start or completion of the pilot examination at a test center.

Under no circumstances will the NBME be liable for any damages or costs that may result in any way from participation in the pilot or from a participant's use of the information derived from participation in the pilot.

The sites that are currently open for registration are as follows:

Boston Downtown Marriott l October 27, 2015 l 10:00 am - 2:30 pm    REGISTER HERE
Boston Downtown Marriott l October 27, 2015 I 5:15 pm - 9:45 pm      REGISTER HERE

Chapel Hill
Univ of North Carolina, Chapel Hill l October 25, 2015 l 1:00 pm - 5:30 pm   REGISTER HERE

New York
Icahn Mt. Sinai School of Medicine l October 16, 2015 l 1:00 pm - 5:30 pm   REGISTER HERE

Jefferson (Locust or Walnut Street Site) l October 17, 2015 l 9:00 am - 1:30 pm   REGISTER HERE 
Jefferson (Locust or Walnut Street Site) l October 24, 2015 l 9:00 am - 1:30 pm   REGISTER HERE Jefferson (Locust or Walnut Street Site) l October 31, 2015 l 9:00 am - 1:30 pm   REGISTER HERE

Washington, DC
Georgetown University SOM l October 23, 2015 l 2:30 pm - 7:00 pm   REGISTER HERE


There are two examinations within the Clinical Research Pilot Assessment. They are differentiated by the responsibilities and knowledge covered within each examination.

The first examination in the Clinical Research Pilot Assessment is for individuals responsible for:

  • Overseeing the progress and conduct of a trial at a site or sites
  • Assessing and ensuring site feasibility and qualifications of site personnel
  • Providing regulatory guidance and oversight
  • Promoting and ensuring protocol compliance
  • Ensuring that adverse events are identified, collected, and reported appropriately
  • Ensuring that data are collected, recorded, and safeguarded correctly
  • Managing the control and dispensing of investigational products

These responsibilities are usually within the job descriptions of clinical research associates (sponsor-designated study monitors), clinical research coordinators, or clinical research managers.

The second examination is for individuals responsible for:

  • Performing study-related procedures and/or making study-related decisions as a site sub-investigator, site investigator, or a principal investigator
  • Ensuring the ethical conduct of the research as the investigator in a study
  • Overseeing a clinical research study as a principal investigator to ensure protection of human subjects' rights, safety and welfare; compliance with the protocol; and adherence to institutional, state, and federal regulations
  • Providing medical oversight in a study as a medical monitor

These responsibilities are typically within the scope of physicians-in-training and of physicians involved in research in their practices, institutions, or CRO/Sponsor employers.

The 4 hour and 30 minute test day will consist of the following:

  • 15-minute tutorial
  • 5 blocks of questions in multiple choice format
  • 15 minutes of break time at midpoint
  • brief post-test survey to obtain examinee feedback

Read the Clinical Research Program bulletin for more information about content categories, feedback and scoring. 


The NBME is providing the materials presented in this pilot assessment for personal or organizational use only. The materials are owned and copyrighted by the NBME. The materials may not be transferred or reproduced in any way. Any unauthorized reproduction of these materials, by any means, including but not limited to, storage in a retrieval system, transmission, printing, memorization, or distribution is strictly prohibited.Organizations will receive aggregate data reports.