Tuesday September 20, 2016 at 12:00 PM EDT
Friday September 23, 2016 at 1:00 PM EDT

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Hilton Hotel-Downtown Cleveland, OH
100 Lakeside Avenue East
Cleveland, OH 44114

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Charlene Mitchell 
Case Western Reserve University
National Center for Regenerative Medicine 

CSC 2016 will feature renowned keynote speakers and leaders in the field of cancer stem cell research. CSC 2016 is guaranteed to offer cutting-edge presentations in a variety of specialized areas within the field. Join us for this 4-day summit and network with scientists and clinicians advancing cancer stem cell research and therapeutic applications. 

Preconference Workshop (Trainee Career Development)

Discussion of grant opportunities, career options, women and underrepresented minority-specific issues. Participants include representatives from NIH institutes' training office, Scientific Review Officers, and junior/senior faculty members.

Conference Debate

Cancer Stem Cells: Fact or Fiction

Session Topics

  • Clinical Trials
  • Epigenetics & Genomics
  • Meet the Editors
  • Development
  • Immunology
  • Tumor Microenvironment
  • Metastasis
  • Heterogeneity and Therapeutic Resistance
  • General & Emerging Concepts

Confirmed Keynotes & Invited Speakers

John E. Dick, PhD
University Health Network, Canada 

Luis Parada, PhD
Memorial Sloan-Kettering

Robert Weinberg, PhD

Irving L. Weissman, MD
Stanford University

Mina J. Bissell, PhD
Lawrence Berkeley 

Connie J. Eaves, PhD
BC Cancer Agency

Thomas Gajewski, MD, PhD
University of Chicago

Carla F. Kim, PhD
Boston Children's Hospital

Ross Levine, MD
Memorial Sloan Kettering

Matthew G. Vander Heiden, MD, PhD

Marius Wernig, MD, PhD
Stanford University

Antonio Iavarone, MD
Columbia University

Max S. Wicha, MD
University of Michigan

Jeffrey M. Rosen, PhD
Baylor College of Medicine

Tannishtha Reya, PhD
University of California, San Diego

Catherine O'Brien, MD, PhD
University of Toronto

Benjamin T. Spike, PhD
University of Utah

Keith Chan, PhD
Baylor College of Medicine

Geoffrey Wahl, PhD
Salk Institute

Fumni Olopade, MD
University of Chicago

Teodoro Pulvirenti, PhD
Nature Cell Biology

Deborah J. Sweet, PhD
Cell Stem Cell

Nywana Sizemore, PhD

Peter Dirks, MD, PhD
Hospital for Sick Children, Toronto

Simona Parrinello, PhD
Imperial London College

Dean W. Felsher, MD, PhD
Stanford University

Daniel Gallahan, PhD

Dean G. Tang, MD, PhD
Roswell Park Cancer Institute

Sunitha Nagrath, PhD
University of Michigan

Michael Espey, PhD

Ming Lei, PhD

Jonathan Pachter, PhD
Verastem, Inc.

2014 Cancer Stem Cell Conference Proceedings

Cancer stem cells: Targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance. Adorno-Cruz V1, Kibria G1, Liu X1, Doherty M1, Junk DJ1, Guan D2, Hubert C3, Venere M4, Mulkearns-Hubert E5, Sinyuk M5, Alvarado A5, Caplan AI6, Rich J7, Gerson SL8, Lathia J9, Liu H10. Cancer Res. 2015 Mar 15;75(6):924-9. doi: 10.1158/0008-5472.CAN-14-3225. Epub 2015 Jan 20.

With the goal to remove the roots of cancer, eliminate metastatic seeds, and overcome therapy resistance, the 2014 inaugural International Cancer Stem Cell (CSC) Conference at Cleveland, OH, convened together over 320 investigators, including 55 invited world-class speakers, 25 short oral presenters, and 100 poster presenters, to gain an in-depth understanding of CSCs and explore therapeutic opportunities targeting CSCs. The meeting enabled intriguing discussions on several topics including: genetics and epigenetics; cancer origin and evolution; microenvironment and exosomes; metabolism and inflammation; metastasis and therapy resistance; single cell and heterogeneity; plasticity and reprogramming; as well as other new concepts. Reports of clinical trials targeting CSCs emphasized the urgent need for strategically designing combinational CSC-targeting therapies against cancer.

2015 American Association for Cancer Research.