Please join us for a free event for the scientific community — graduate level and higher — at the Simons Foundation, located on 21st Street in Manhattan. Limited seating is available on a first-come, first-served basis. We encourage you to obtain tickets online now. Search by series or speaker, view the monthly calendar and access video on simonsfoundation.org.
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AUTISM: EMERGING CONCEPTS
What Can Genetics Tell Us About Autism Spectrum Disorder? Wednesday, March 22, 2017 Speaker: Stephan J. Sanders 4:15PM Tea; 5:00PM Lecture |
Stephan Sanders trained as a pediatric physician in the United Kingdom before pursuing a research career in genomics and bioinformatics. His work has helped characterize the role of de novo mutations in the etiology of autism and identified multiple autism risk loci, including duplications of the 7q11.23 Williams syndrome region (Sanders et al. Neuron 2011) and mutations in the sodium channel gene SCN2A (Sanders et al. Nature 2012). His work on the integration of copy number variation and exome data across multiple autism cohorts recently identified 71 autism risk loci (Sanders et al. Neuron 2015). In addition, he worked as part of a group that integrated spatiotemporal gene expression data from the human brain with these autism-associated genes (Willsey et al. Cell 2013). This approach has implicated deep-layer glutamatergic neurons in the frontal cortex during mid-fetal development in the causation of autism. His lab has three main research aims: 1) Understanding the genetic basis of childhood neurodevelopmental conditions, in particular autism; 2) Understanding how these genetic factors lead to the conditions; and 3) Understanding the mechanism that leads to the male bias in autism diagnosis, in particular through identifying the biological basis of the female protective effect. |
The Gerald D. Fischbach Auditorium offers accessible seating to patrons with special access needs. Please fill out the special accommodations request when ordering your ticket online. Most events in the auditorium are video recorded by the organizer, and many are photographed. The resulting media may be used by the event organizer(s) on its website(s), or elsewhere. Audio or visual recording and photography by attendees is not permitted without prior approval of the organizer. |
Gerald D. Fischbach Auditorium
Simons Foundation 160 Fifth Avenue at 21st Street, 2nd Floor New York, NY 10010 |
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